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Global Journal of Physical Chemistry. Volume 1, Issue 1 (2010) pp. 79-90
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Review Article
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Electrogenerated Chemiluminescence for bio-assay: from single Molecule to Nano-structured tracers
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Simone Zanarinia,Leopoldo Della Cianab, Vijaykumar S. Ijeria, Jijeesh R. Naira, Claudio Gerbaldic*
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aDepartment of Materials Science and Chemical Engineering, Politecnico di Torino, C.so Duca degli Abruzzi 24, 10129 – Turin, Italy
bCyanagen s.r.l., Via Stradelli Guelfi, 40/c, 40138 – Bologna, Italy
cIIT@POLITO Center for Space Human Robotics, IIT-Italian Institute of Technology, Corso Trento 21, 10129 – Turin, Italy
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Abstract |
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This review provides a basic
introduction to the Electrogenerated Chemiluminescence (ECL) technique. The
fundamental concepts, mechanisms and bio-analytical applications are briefly discussed.
In addition, the trends of current ECL materials research are summarized in
relation to their potential use in biological systems. Particular emphasis is
given to new water soluble ECL labels and to encapsulation of emitting materials
in nano-structures including silica nanoparticles, carbon nanotubes and quantum
dots.
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Keywords |
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Electrogenerated chemiluminescence; Bio-assay; Nanostructured tracer; Ir(III)/Ru(II) complexes;SiO2 nanoparticles
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