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  Global Journal of Surgery. Volume 1, Issue 2 (2010) pp. 104-108
  Research Article
 
A young man with advanced gastric carcinoma and liver metastases is tumor free five years after combined palliative gastrectomy, palliative chemotherapy and thermoablation - a case report
  Yves Dittmar*, Falk Rauchfuss, Rigo Voigt, Götz, Max, Karin Jandt and Utz Settmacher  
     
Department of General, Visceral and Vascular Surgery, University Hospital Jena, Erlanger Allee 101, 07747 Jena, Germany
   
  Abstract  
  We report the case of a young patient with intestinal type advanced gastric cancer and bilateral liver metastases who is tumor free for more than five years now. Only few cases of long term survival in hepatic metastasized gastric cancer have been reported in the literature.The 32 years old male patient presented with liver metastases in both liver lobes two months after curative gastrectomy for locally advanced gastric cancer. He underwent four applications of percutaneous thermoablation within 18 months and palliative chemotherapy. He is now tumor free and in excellent physical condition for five years and might be considered as being cured. Genome-wide DNA analysis of the cancer tissue showed only few chromosomal aberrations. Our presented case shows that curation in selected patients with stage 4 gastric cancer is not definitely impossible. Patients with young age, limitied involvement of secondary organs and low degree of chromosomal aberrations should be candidates for multimodal treatment and extended palliative surgery.
     
  Keywords  
  Gastric cancer; Liver metastases; Chromosomal aberration; Multimodal treatment; Gastric resection; Long term survival  
     
   
   
   
   
     

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