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Global Journal of Surgery. Volume 2, Issue 1 (2011) pp. 37-45
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Research Article
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Assessment of Daflon 500 mg in ameliorating symptoms after ligasure hemorrhoidectomy for prolapsed hemorrhoids:
A controlled randomized study
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Mahmoud F. Sakr*
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Department of Surgery, Faculty of Medicine, University of Alexandria, Egypt
Ahmadi Hospital, KOC, Kuwait
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Abstract |
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Objective: To evaluate if micronized purified flavonoid fraction (MPFF) (Daflon) ameliorates symptoms after Ligasure hemorrhoidectomy (LH) for prolapsed hemorrhoids. Experimental: Eighty eight patients with prolapsed hemorrhoids who underwent LH were randomly assigned to receive either, analgesics and Metronidazole postoperatively (n=45) or MPFF in addition (n=43). Data on patient demographics, postoperative course and complications were prospectively collected. Post-operative symptoms (pain, bleeding, mucus discharge, pruritis, and tenesmus) were assessed regularly for 8 weeks. Each symptom was allocated a score from 0 to 4. A global score was constructed to compare improvement in symptoms between groups at weeks 1 and 8 postoperatively. Results and Discussion: All symptoms were significantly better relieved in the Daflon group during the first week post-LH. The global score for each symptom was significantly lower in the Daflon group. Conclusions: MPFF (Daflon) can significantly reduce the intensity and duration of postoperative symptoms after LH for prolapsed Grades III and IV hemorrhoids.
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Keywords |
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Hemorrhoids; Prolapse; Hemorrhoidectomy; Ligasure; Micronized purified flavonoid fraction (MPFF); Daflon
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