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  Chemical Sensors 2011, 1: 17
  Research Article
Electrochemical analysis of daunorubicin - nucleic acid interaction at disposable electrode
  Gulsah Congur, Ayfer Caliskan, Arzum Erdem  
Ege University, Faculty of Pharmacy, Analytical Chemistry Department, Bornova, 35100 Izmir, Turkey
  Daunorubicin (DNR) is an anticancer drug which is widely used for treatment of acute myeloblastic leukemia (AML) and acute lymphoblastic leukemia (ALL). Disposable electrochemical sensors were used in our study to detect DNR-nucleic acid interactions by differential pulse voltammetry (DPV). For surface confined interaction between DNR and DNA, electrochemical impedance spectroscopy (EIS) was applied and results were compared with those from DPV.
  Daunorubicin; Electrochemical; Biosensor; DNA-drug interactions  

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