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  Chemical Sensors 2012, 2: 7
  Research Article
Preparation of NiO/ZnO hybrid nanoparticles for electrochemical sensing of dopamine and uric acid
  Sathish Reddya, B. E. Kumara Swamya, S. Arunaa, Mohan Kumara, R. Shashankaa, H. Jayadevappab  
a Department of P. G. Studies and Research in Industrial Chemistry, Kuvempu University, Jnana Sahyadri, Shankaraghatta, Shimoga, Karnataka 577451, India
b Department of Chemistry, Sahyadri Science College, Shimoga, Karnataka, India

  The NiO/ZnO hybrid nanoparticles were synthesized using sodium dodecyl sulfate (SDS) in a micro-emulsion method. The NiO/ZnO hybrid nanoparticles were characterized using X-ray diffraction, scanning electron microscopy, UV-visible absorption spectroscopy, infrared absorption spectroscopy and energy dispersive X-ray spectrum. The obtained NiO/ZnO hybrid nanoparticles were used for the preparation of modified carbon paste electrode (MCPE) for electrochemical detection of dopamine and uric acid at physiological pH 7.4. The MCPE exhibits enhanced electrochemical parameters such as peak current response, surface area of electrode, electrocatalytic activity, diffusion-coefficient, lower detection limit, sensitivity and higher linear range. The proposed method was successfully applied for the detection of dopamine and uric acid in real samples.
  NiO/ZnO hybrid nanoparticle; Carbon paste electrode; Dopamine; Uric Acid; Cyclic Voltammetry; Differential pulse voltammetry  

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