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  Chemical Sensors 2014, 4: 5
  Research Article
 
Development of sensitive glucose sensor using CuO functionalized carbon nanotubes based nanochip
  M. Willandera, K. Khuna, X. Liub, J. Lub, W. Khalidc,d,e, Z. H. Ibupotoa  
     
a Physical Electronics and Nanotechnology Division, Department of Science and Technology, Campus Norrköping, Linköping University, SE-60174 Norrköping, Sweden
b Department of Physics, Chemistry, and Biology (IFM), Linköping University, 58183 Linköping, Sweden
c Chalmers Industrial Technologies, Gothenburg, Sweden
d Jadoo Technologies Inc. , Toronto, ON, Canada
e Lawrence Berkeley National Labs, USA

   
  Abstract  
  In this work, multiwall carbon nanotubes (CNTs) grown on a silicon chip are functionalized with the leaf-like morphology of copper oxide (CuO) and are effectively used for the development of sensitive glucose sensor by immobilizing glucose oxidase on hybrid CuO/CNT structures. The CuO functionalization of carbon nanotubes was characterized by transmission electron microscopy (TEM) and X-ray photoelectron spectroscopy (XPS). The CuO nanoleaf was firmly bound to the carbon nanotubes and the hybrid materials were only composed of CuO and carbon nanotubes. The glucose oxidase was physically adsorbed on the CuO functionalized carbon nanotubes which further resulted as a sensitive, selective, stable, repeatable and reproducible glucose biosensor. The sensitivity of the proposed sensor was found to be 64.5 mV/decade and a fast response time of less than 10 s. The results obtained in this study indicate a novel hybrid nanomaterial (CuO/CNT) glucose sensor on a chip for monitoring different concentrations of glucose from pharmaceutical and biomedical applications.
     
  Keywords  
  Copper oxide; Carbon nanotubes; Potentiometric; Glucose sensor  
     
   
   
   
   
     

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