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Journal of Nanoscience Letters. Volume 1, Issue 3 (2011) pp. 145-165
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Review Article
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AuNPs are toxicin vitro and in vivo: a review
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S. Sabella, A. Galeone, G. Vecchio, R. Cingolani, P. P. Pompa
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Italian Institute of Technology, Center for Bio-Molecular Nanotechnology,
Via Barsanti - 73010 Arnesano (Lecce), Italy
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Abstract |
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In this work we reviewed recent findings about the toxicity of gold nanoparticles (AuNPs) in in vitro and in vivo experiments. We show that, beyond the wide variability of the experimental conditions (including physical/chemical AuNPs characteristics) and a slight discrepancy of some published results, as-synthesized (naked) AuNPs are significantly toxic both in vitro and in vivo, while appropriate coating may partially prevent their harmful effects.
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Keywords |
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Gold nanoparticles; Nanotoxicity; In-vitro studies; In-vivo studies
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