creating knowledge for future



High Quality


Scholarly Publishing
                CAREER NETWORK  
         
World's one of the largest Research
Career Network
Benefits
  •     Academic & Industry jobs
  •     Project funding
  •     Visiting faculty positions
  •     Visiting scientist positions
  •     Invited talks
  •     and more...  
   
Register FREE  
 
 
 
 
 
  Journal of Spectroscopy and Dynamics 2013, 3: 1
  Research Article
 
Pressure-tuning infrared and Raman studies of polymorphism in pharmaceutical compounds: Progesterone
  Gisia L. Pisegna, Ian S. Butler  
     
Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, Quebec, Canada H3A 2K6
   
  Abstract  
  The IR and Raman spectra of the two polymorphic forms, I and II, of progesterone (pregn-4-ene-3,20-dione) have been examined under high pressures up to about 50 kbar using a diamond-anvil cell. Both polymorphs undergo structural changes in the 15-20 kbar pressure range. There is no convincing evidence for the conversion of form II into the more thermodynamically stable form I.
     
  Keywords  
  Polymorphism; Pharmaceutical compounds; High pressure; Diamond-anvil cell; IR and Raman spectroscopy  
     
   
   
   
   
     

  © 2016 Cognizure